Cohance Lifesciences Limited
8,564words
12turns
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Key numbers — 40 extracted
rs,
40%
38.7%
5%
34.8%
101%
11%
2x
29%
17%
99.99%
Rs 2.9
Guidance — 4 items
Other notable statistics include
opening
“Operating leverage will drive EBITDA margin expansion in medium term ADC Manufacturing Process Payload Linker & P/L synthesis Bio- conjugation End-to-end Integrated CRDMO Discovery Preclinical Phase 1 Phase 2 Phase 3 Commercial India + US footprint”
What will accelerate the base growth
opening
“BD efforts; target to add 7+ new products in FY25 Outlook: In-line with earlier expectation, expected to deliver full year launches and market demand growth backed by new product recovery.”
Note
opening
“we At a combined platform anticipate level, growth in the second half of FY25, and growth acceleration from FY26 onwards.”
Note
opening
“58% With a strong order book visibility, Cohance remains well-positioned to drive growth in FY25.”
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Risks & concerns — 1 flagged
These products segments have less concentration risk and limited pricing pressure.
— What will accelerate the base growth
Speaking time
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Opening remarks
Combined Business
Proforma Metrics Proforma Merged Entity 9MFY25 INR Mn Revenue Adjusted EBITDA Adjusted EBITDA margin % Adjusted PAT Adjusted PAT margin % RoCE RoE (Net Debt) / Net Cash to Adj. EBITDAx 7,956 3,372 42.4% 2,465 31.0% 24.9% 13.4% 0.5X 9,735 2,777 28.5% 1,513 15.5% 26.8% 23.0% (0.4)X Merged Company Merged Company 17,691 6,141 34.8% 3,978 22.5% 25.8% 13.4% 0.0X Note: 1) Adjusted EBITDA includes One-time adjustment for ESOP, Merger and acquisition costs Rs.594 mn and Rs.329 mn for 9MFY24 & 9MFY25 respectively. Source: Cohance LifeSciences Website published Investor Presentation Pg. 14 Proforma Merged Entity - Combined business mix 9MFY25 Sales Mix (9MFY25) Manufacturing Facilities (Regulatory approved) R&D Centers Formulations & Others 20% 6 (2) 3 Merged Company Merged Company CDMO 80% CDMO 30% API++ 70% API++ 48% CDMO 52% 8 (5) 4 14 (7) 7 Capacity ~1,400 kL ~1,250 kL ~2,650 kL Source: Cohance LifeSciences Website published Investor Presentation Pg. 15
Combined Business
Key segment wise strategy Our Growth Engines – Pharma CDMO key driver Small Molecules, ADCs, Oligonucleotides and Peptides constitute ~52% of New Drug Additions to the Global Preclinical and Clinical Pipeline in 20241 Pharma CDMO 53%# of Sales Specialty Chemicals 7% of Sales • Strategic Business Unit to focus on growth acceleration by adding new customers and new products. • Dedicated site (Vizag), Space for future expansion. • Relationships with innovators in AgChem, Cosmetics, Electronic Chemicals and Photochromic Lens. • Focused portfolio and market leadership in low-mid volume, specialty APIs with low competitive intensity • Ongoing augmentation of new product pipeline. • Built deep cost position through backward Small Molecules ADC* • • • 16 Commercial Patented molecules 14/20 Top innovator relations; contributing >80% revenues 7 molecules in Phase-3 translating into 12 intermediates; RFQs growing 2.2x Payload –linker – Bioconjugation • Two unique commercial ADCs supplies • Expand
Other notable statistics include
• Cancer remains the dominant focus of drug developers, with 30% novel approvals in 2024. • • • • Biologic approvals stay constant at 30-35% per year 52% received Orphan Drug Designation for treating rare diseases. 36% were designated Breakthrough designation. 56% received priority review, a regulatory designation for therapies that ‘significant improvements over the standard of care. the FDA expects to offer The positive trend continues in 2024: In 2024, 50 novel drugs were approved by FDA, of which 34 were small molecules (68%), which includes two Oligos, one Peptide and one Radiopharma Source: Citeline Pg. 20 Suven is present in the fast growing tech platforms of ADCs & Oligos CDMO Market by Technology – Market Size and Projected Growth (2023-29) ) 9 2 - 3 2 0 2 ( h t w o r G t e k r a M d e t c e p x E 40.00% 35.00% 30.00% 25.00% 20.00% 15.00% 10.00% 5.00% 0.00% -5.00% Suven High-Growth Technology Platforms ADC ($2.7 Bn) Protein Degraders (~$100 Mn) Cell and Gene Therapy Oligonucle
Note
(1) P–L = Payload – Linker, (2) CY= Calendar Year “January to December” Pg. 25 Expansion of ADC - CDMO Market share for Suven+Cohance platform via NJ Bio Suven’s Addressable Market expands 7x (US$200mn to US$1.4bn), post-acquisition. Suven Platform and NJ Bio’s relevant addressable market is slated to grow from US$1.4bn to US$4bn (23%+ CAGR) Addressable market size(US$1.36Bn) Addressable market size(US$3.88Bn) Expansion of Addressable Market • Acquisition expands the serviceable market for late is presently which Cohance phase/Commercial Payloads in • Supply to Early-Stage Payload along with addition of novel offerings like Linkers and Bioconjugation Source: Industry Data Market Share within Existing Segments • Enables Suven+Cohance to tap the customer early and maintain continuity of supply New Opportunities: Bioconjugation and Linkers at Commercial Phase • NJ Bio’s Linker and Bioconjugation capabilities are confined to early stage due to lack of GMP experience • Combination with Coha
What will accelerate the base growth
Portfolio is unique and can drive sustained growth o Business model focus is on small-mid volume APIs. These products segments have less concentration risk and limited pricing pressure. o Focus on expanding market share on the back of deep cost position backed by backward integration • Continue to be amongst the Top 3 players for most top molecules (8/10) o Capabilities to handle a drug end-to-end throughout its lifecycle $101+ Bn Total Addressable Market Sustained growth Sustained growth Merchant API market revenues*, Euro 91 95 100 106 113 117 Higher product validations over 18-24 months; well supported by our 2023 2024 est. 2025 est. 2026 est. 2027 est. 2028 est. BD efforts; target to add 7+ new products in FY25 Outlook: In-line with earlier expectation, expected to deliver full year launches and market demand growth backed by new product recovery. Source: Cohance investor presentation Small molecules continue to be a significantly large proportion of Merchant API market reven
Ag-chem
As indicated, we have seen strong sequential recovery in this business segment. Our concerted BD efforts and early benefits of SBU strategic focus yielding results. We’re seeing new product discussions and fresh RFQs including from potential new customers and existing strategic partnerships. Development and Commercial manufacturing with focus on intermediates and AIs Flexible capacity - Dedicated site for AgChem (Vizag), Space for future expansion, Kilo / Pilot scale facility available Improved processes, introducing EHS Best Practices Spec Chem Relationships with Originators in Cosmetics, Electronic Chemicals, Photochromic Lens and Energy Industries Successfully delivered innovator projects from gram to multi kilo scale Amongst India’s leading manufacturers of high purity electronic chemicals; Highly backward integrated Source: Cohance investor presentation Pg. 28 Pg. 28 Update on Amalgamation of Suven Pharmaceuticals with Cohance Lifesciences Suven Pharma – Cohance
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