SHILPAMEDNSE10 February 2022

Shilpa Medicare Limited has informed the Exchange about Investor Presentation

Shilpa Medicare Limited

Shilpa Medicare Limited Corporate & Admin Office: “Shilpa House”, # 12-6-214/A-1, Hyderabad Road, Raichur – 584 135, Karnataka, India Tel: +91-8532-238704, Fax: +91-8532-238876 Email: info@vbshilpa.com, Web: www.vbshilpa.com CIN: L85110KA1987PLC008739

10 February 2022

National Stock Exchange of India Limited, Exchange Plaza, 5th Floor, Plot No. C/1, G Block, Bandra Kurla Complex, Bandra (E), Mumbai-400 051

Corporate Relationship Department, BSE Limited, Phiroze Jeejeebhoy Towers, Dalal Street, Fort, Mumbai-400 001

Dear Sir/Ma’am,

Sub: Investor Presentation of the Company for the Quarter ended 31 December 2021

Ref.: Disclosure under Regulation 30 of SEBI (Listing Obligations and Disclosure Requirements)

Regulations, 2015

Scrip Code: BSE - 530549/Stock Symbol: NSE – SHILPAMED

We wish to inform you that Investor Presentation of the Company for the Quarter ended 31 December 2021 with regard to financial performance, discussion on Business and other updates is attached herewith.

We request you to take the same on record.

Thanking you.

Yours faithfully, For Shilpa Medicare Limited

V.V. Krishna Chaitanya Company Secretary & Compliance Officer

Shilpa Medicare Limited (SML)

Q3 FY22 Results Presentation

1

2

API Units, Raichur

Disclaimer

are

subject

to certain risks

in this document may be Certain statements forward-looking statements. Such forward looking and statements uncertainties like regulatory changes, local political or economic developments, and many other factors to differ that could cause our actual materially from those contemplated by the relevant forward-looking Shilpa Medicare statements. Limited (SML) will not be in any way responsible for any action taken based on such statements and undertakes no obligation to publicly update these forward-looking statements to reflect subsequent events or circumstances.

results

Company Overview

3

Established presence in Active Pharmaceutical Ingredients (APIs) and Formulations for domestic & international markets

Pursuing niche growth businesses like Biologics, Transdermal & Oral Dissolving Films Formulations

Affordable & Effective Pharmaceutical Solutions

Robust research orientation resulting in innovative products

Very strong R&D background including development, pathway engineering and characterization of biologics

Best in class manufacturing and supply of high-quality affordable drugs

Table of Contents

4

Financial Performance........................................05

Discussion on APIs/Formulations/New Segments……09/15/19

Other Updates.................................................21

Financial Performance

5

Abridged P&L Statement - Consolidated

6

(Rs. In Lakhs)

Particulars

Q3 Y22 Q3 FY21 Change (%) 9M FY22 9M FY21 Change (%)

Total Income (I+II) I. Total Revenue from Operations (A+B+C+D)

•API (A) •Formulations (B) •Service Revenue / Product License Fees (C) •Others (D) II. Other income Total Expenditure EBITDA EBITDA margin (%) Exceptional Income PBT PAT Share of Profit/(Loss) of Non-Controlling Interest

PAT after Share of profit/(loss) of Non controlling interest

27,778 27,230 18,195 7,823 711 501 548 22,724 5,054 18% - 1,996 1,025 (73)

19,986 19,125 13,533 4,071 1,185 337 861 17,028 2,958 15% - 1,106 814 (47)

956

767

39 42 34 92 (40) 49 (36) 33 71

- 81 26 -

25

81,368 80,493 50,216 25,715 2,876 1,686 875 67,487 13,881 17% 891 5,845 3,363 (255)

71,634 69,305 46,128 18,048 3,018 2,112 2,329 53,765 17,869 25% 6,084 18,803 13,998 (65)

3,111

13,936

14 16 9 42 (5) (20) (62) 26 (22)

(85) (69) (76) 292

(78)

Abridged P&L Statement - Standalone

(Rs. In Lakhs)

7

Particulars

Q3 FY22

Q3 FY21

Change (%)

9M FY22

9M FY21

Change (%)

Total Income (I+II) I. Total Revenue from Operations (A+B+C+D) •API (A) •Formulations (B) •Service Revenue / Product License Fees (C) •Others (D) II. Other income Total Expenditure EBITDA EBITDA margin Exceptional Income PBT PAT

28,964

27,664

18,195 8,276

383

810 1,300 22,008 6,956 24% - 4,835 3,677

17,990

17,129

12,782 3,509

502

337 861 14,061 3,929 22% - 2,487 1,687

61

62

42 136

(24)

140 51 57 77

- 94 118

83,476

80,284

50,216 26,895

1,487

1,686 3,192 64,204 19,272 23% 891 14,078 10,554

66,938

65,061

43,998 16,893

2,053

2,118 1,876 46,095 20,842 31% 5,295 22,031 15,780

25

23

14 59

(28)

(20) 70 39 (8)

- (36) (33)

In relation to the import alert issued by the USFDA for the Jadcherla unit, the Company has initiated extensive remedial measures. The incremental costs incurred on account of the USFDA import alert is Rs 474 Lakhs in Q3 FY22 & Rs. 2,760 Lakhs

Managing Director’s Message

8

Commenting on Q3 FY’22 performance, Mr. Vishnukant Bhutada, Managing Director Shilpa Medicare Limited said,

““Momentum in API business continues to improve in line with the measures we have taken, which is heartening. We have a deep pipeline of products that will help us maintain a positive outlook in this segment. In Formulation business, we are making progress in our engagement with the regulator and simultaneously have been carrying out new filings. Our team has been working collaboratively with the external consultants in order to achieve remediation. Meanwhile I am happy to share that we have successfully implemented site transfer for 2 products de-risking our business from single site dependency. We remain committed to normalize our US market operations at the earliest while we continue to enhance our reach in other key geographies.

I am pleased to share that we are working with Mylab Discovery Solutions Pvt Ltd to manufacture ‘Sputnik Light Drug Substance’ for them. Along with this we have initiated our manufacturing arrangements for the manufacture of ZyCoV-D. Additionally, we have made healthy progress on our own portfolio of products with very robust results in our clinical & animal trials for Adalimumab & Aflibercept respectively.

In a another significant development during the quarter, we have successfully raised Rs. 297 cr. through private placement of our shares to marquee investors. This fund raise has helped us in correcting the leverage position of the company while continuing with our growth impetus.”

Discussion of API Segment

9

Perspectives on APIs

10

Key strengths of the business

• Wide range of Oncology & Non oncology niche product portfolio • Building capacity & capability to improve efficiency & reach • Continuous improvement in process, operation & development to improve the yield , quality & compliance to maintain

leadership position in key molecules

• Positioned business development teams in all the regions globally • Strong R&D with focus on difficult to synthesize products including development of newer business segments

Way forward

• Separate business under a separate subsidiary to provide focused approach resulting in better operating efficiency with fund raising opportunity in the segregated business either from strategic investors through private placement or from investors at large through public issue

• Greater impetus to specialty areas of CDMO, Peptides, Polymers & intermediate with early success signs • Continuous efforts on process optimization & efficiency improvement

API REVENUE HIGHLIGHTS

11

Rs. In Lakhs

12,000

10,000

8,000

6,000

4,000

2,000

-

Q2 FY22 Q3FY22 Q3 FY21

Oncology 11,352 10,679 7,423

Non-Oncology 4,730 5,112 2,367

Crams 2,972 2,403 2,992

Product wise DMF filings as on December 31, 2021

12

Name of the API

US FDA

EU/ EMEA

TPD-Canada

PMDA Japan

TGA & Medsafe-NZ

EDQM

KFDA Korea

GCC & ROW

WHO Market

Ambroxol HCl Azacitidine Bicalutamide Bendamustine HCl Bortezomib Busulfan Capecitabine Decitabine Erlotinib HCl Fingolimod HCl Gemcitabine HCl Imatinib Mesylate Letrozole Irinotecan HCl Irinotecan HCl (Process-2) Melphalan HCl Oxaliplatin Pemetrexed Disodium Temozolomide Zoledronic Acid Pemetrexed Dipotassium (Nonahydrate) Anastrozole

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Product wise DMF filings as on December 31, 2021

13

Name of the API

US FDA

EU/ EMEA

TPD-Canada

PMDA Japan

TGA & Medsafe-NZ

EDQM

KFDA Korea

GCC & ROW

WHO Market

Clofarabine Dimethyl Fumarate Axitinib Enzalutamide Pirfenidone Gemcitabine Hydrochloride (Process-2) Ibrutinib Teriflunomide Pomalidomide Tranexamic Acid Thalidomide Sunitinib Malate Lenvatinib Mesylate Tenofovir Alafenamide Fumarate Praziquantel

Tenofovir Disoproxil Fumarate

Cyclophosphonamide Prucalopride succinate Lenalidomide Acebrophylline Sorafenib (Base) Sunitinib (Base)

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Product wise DMF filings as on December 31, 2021

1414

Name of the API

US FDA

EU/ EMEA

TPD-Canada

PMDA Japan

TGA & Medsafe-NZ

EDQM

KFDA Korea

GCC & ROW

WHO Market

Nifedipine Phenylephrine hydrochloride Nilotinib Varenicline tartrate Cabazitaxel Glycopyrronium bromide

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Discussion of Formulations Segment

15

Perspectives on Formulations

16

Key strengths of the business

• Vertically integrated backed by in-house R&D and innovative APIs with sharp cost competencies • Range includes liquid and lyophilized injectable, sterile dry powder injections and oral solids in onco & adjuvant

therapies

• Strong portfolio of NDDS/value added product pipeline • Targeted sales of complex products in key regulated/RoW markets

Way forward

• Partial remediation towards USFDA import alert complete

• Submission of MCAP (Compliance Plan) to FDA in Q4 • Continue the hedging strategy to de-risk against single site operations • Continue focus on niche and value-added products portfolio development

• Strong strategic partnership model to enhance reach

Formulation - Highlights

Revenue Split

(Rs. In Lakhs)

17

Q3 FY22

50 , 1% 450 , 5%

210 , 3% Q2 FY22

377 , 4%

2,246 , 27%

USA'

EUROPE

ROW

DOMESTIC

5,529 , 67%

3,220 , 37%

USA'

EUROPE

ROW

DOMESTIC

4,925 , 56%

Q3 FY21

91 , 2%

21 , 1%

427 , 12%

2,969 , 85%

USA'

EUROPE

ROW

DOMESTIC

Rs. 8,276

Rs. 8,732

Rs. 3,509

• Completed 2 site transfer projects • Won 2 year tender for supply of Dimethyl Fumurate in Saudi Arabia through partner • Received approval for Pemetrexed RTU for the EU market • Remote record review by USFDA of QC Lab at Bangalore successfully completed without any observations

Formulation Product Pipeline as on December 31, 2021

18

Regulatory Submissions

- US ANDA: SML

- US NDA: SML

- US ANDA: Customers

TOTAL (In US)

- EU Filing

- Row Filling

TOTAL (In EU & ROW)

GRAND TOTAL

Filings

Approved

(Including Tentative)

Pending

26

03

18

47

25

279

304

351

13

01

13

27

19

95

114

141

13

02

05

20

06

184

190

210

18

Discussion of Biologicals

19

Perspectives on Formulations

20

Key strengths of the business

• Strong R&D with focus on difficult products • World class manufacturing facility • Development of 1 NBE and 6 biosimilars in limited competition space with significant cost advantage • 2 products in human clinical & 1 in animal clinicals • Strategic partnerships in vaccine manufacturing

Way forward

• First product launch in India expected in Q3/Q4 of FY22-23 • Strategic tie-ups for the international market • Capture low hanging fruits exploring additional vaccine / MABs manufacturing tie-ups

Other Updates

21

Patents Status as on December 31, 2021

22

Patents

Filings

Granted

Pending

-

-

-

-

API

Formulation*

Films Topical & Transdermal

Biologicals

-

Others

TOTAL

208

182

61

12

22

485

45

35

6

5

5

96

163

147

55

7

17

389

* Formulation numbers includes the Patents of FTF Pharma Pvt Ltd Ahmedabad, a wholly owned subsidiary of Shilpa Medicare Ltd

Manufacturing Excellence

Dharwad

Jadcherla Unit

23

• Biologicals Manufacturing plant &

R&D Facility

• Formulations (Onco & Adjuvant

Therapy

• of Onco – Injectable & Oral)

Bengaluru Unit

Hyderabad

• TDS & ODF Manufacturing Facility

& Formulation R&D

Raichur Unit I & II

Ahmedabad

• API (Oncology – Non-Oncology) • API (Oncology – Non-Oncology)

and R&D API

• CRAMS • Peptide • Polymer

• Formulations (Oral Dissolving Films) • Bio Analytical Lab,

Pharmacovigilance Lab & Quality control lab

• CRO & CDMO • R&D Formulation

About Shilpa Medicare Ltd.

24

Shilpa Medicare Limited (SML) started its operations as API manufacturer way back in 1989 at Raichur, Karnataka- India. Today Shilpa Medicare Limited is a global brand in manufacturing and supplying of affordable API and Formulation globally in different regulated markets.

Shilpa Medicare has been on path of expansion ever since its inception. With a regulatory recognized manufacturing set up and excellent scientific expert team in place, Shilpa Medicare has since been on a steady growth path. Currently they are one of the leaders in the Oncology market and offer a to complete range of products in this segment spanning across APIs, consolidate in field of Oncology, API and formulations, they are striving to put in efforts in field of novel drug delivery systems and biotech products along with widening their focus to other therapy areas. Where Shilpa Medicare Ltd is today is the result of their constant endeavors for more than three decades.

formulations both in terms of R&D and manufacturing capabilities. Further

Siddharth Rangnekar Karl H Kolah

CDR India

+91 22 6645 1209 / 1220

siddharth@cdr-india.com karl@cdr-india.com

25

Thank You

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